Chinese and international scientists have for the first time identified the three gene loci susceptible to laryngeal squamous cell carcinoma (LSCC), according to a statement from the Chinese PLA General Hospital on Wednesday.
The scientists used the method of genome-wide association study (GWAS) to determine the locus. This is the first time GWAS has been applied to laryngeal cancer research, and the successful result was published on the tenth issue of the international journal Nature Genetics in October.
The expert team includes top Otolaryngology-head and neck surgery-practitioners from China and abroad.
From the Chinese side are Doctor Liu Mingbo, Wang Jialing and Yang Shiming from the Chinese PLA General Hospital, Doctor Lin Dongxin, Wuchen from Chinese Academy of Medical Sciences and Doctor Wei Qingyi from Shanghai Medical College of Fudan University.
The team carried out GWAS on 993 laryngeal cancer patients. The study will help early diagnosis and molecular targeting treatment for laryngeal cancer.
(Xinhua News Agency December 3, 2014)